Study Links Roundup Chemical to Long-Term Brain Damage

Study Links Roundup Chemical to Long-Term Brain Damage

Introduction

A recent study suggests that exposure to the widely used herbicide Roundup, which contains the active ingredient glyphosate, may be linked to the development of neurodegenerative diseases such as Alzheimer’s.

What does the study indicate?

Conducted by researchers from Arizona State University and the City of Hope Comprehensive Cancer Center in California, the findings were published on December 4 in the Journal of Neuroinflammation. The study indicates that glyphosate exposure increases brain inflammation in mice, potentially raising the risk of similar conditions in humans.

Roundup's History

Roundup has been a staple in agriculture and residential weed control for decades, marketed as safe for humans. However, growing research connects glyphosate to serious health risks, including non-Hodgkin’s lymphoma and other cancers. Over the years, Bayer and its Monsanto subsidiary have faced more than 120,000 lawsuits claiming glyphosate exposure caused cancer. These legal battles have resulted in over $10 billion in settlements. In response to public outcry, Bayer announced in 2021 that it would remove glyphosate from consumer versions of Roundup, though the chemical remains in formulations used for agricultural purposes.

Impact of exposure on mice

The study explored the impact of glyphosate exposure on mice, revealing that the chemical triggered neuroinflammation and worsened symptoms in mice predisposed to Alzheimer’s disease. Even short-term exposure resulted in long-lasting effects, including heightened brain inflammation, anxiety-like behaviors, and increased early mortality. Notably, these outcomes persisted in mice given six months to recover post-exposure. Researchers attribute these effects to aminomethylphosphonic acid, a metabolite of glyphosate that accumulates in brain tissue.

What did the researchers say?

The study underscores the potential danger of glyphosate in exacerbating neurological conditions. “Our results are the first to demonstrate that, despite an extended recovery period, exposure to glyphosate elicits long-lasting pathological consequences,” the researchers concluded. They emphasize the need for further studies to assess the herbicide's impact on human brain health and its possible role in neurodegenerative diseases.

Raising concerns around Roundup

As glyphosate use continues to rise globally, the findings raise concerns about its broader implications for public health, highlighting the need for more stringent evaluations of its safety and long-term effects.

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